Assistant Professor

Dr. Smitha K R, M.Sc., Ph.D.

Address:  

Dept. of Biochemistry, Sree Krishna College Guruvayur, Thrissur, PIN – 680102, KERALA

Email: smitharkr @gmail.com

Education
  • Ph.D. (Biochemistry):  Amala Cancer Research centre, Amala Nagar, Thrissur (University of Calicut) (2019)
  • M.Sc. (Biochemistry): Kongunadu Arts and Science College, Coimbatore (Bharathiar University, Coimbatore) (2004)
Awards /Fellowship
  • Joint CSIR /UGC-NET for Life Sciences, June 2009
  • GATE 2013
Research interests
  • Cancer Biology, Phytochemistry
Positions Held

Assistant Professor: Dept. of Biochemistry, Sree Krishna College Guruvayur (2015 – Present)

·         Guest Lecturer:  Dept. of Microbiology, St. Mary’s College, Thrissur (2011-2012)

·         Guest lecturer: Dept. of Biochemistry, Sree Krishna College, Guruvayur (2007-2009)

·         Guest lecturer: Dept. of Microbiology, Sree Sankara College, Kalady (2004-2006)

Publications
  1. Desmodium gyrans DC modulates lipid trafficking in cultured macrophages and improves functional high-density lipoprotein in male wistar rats, MS Indu, Arunaksharan Narayanankutty, Smitha K Ramavarma, Jeksy Jose Manalil, Jose Padikkala, Achuthan Chathrattil Raghavamenon, Indian Journal of Pharmacology 53,4 (2021) 286-293
  2. Neera, a non-fermented traditional drink from coconut spadix restores the redox status in sodium fluoride intoxicated mice, Prabha Silpa, Nair Meera, Edappilly M. Shaji, Muralidharan S. Indu, Koyickal Madham R. Smitha, Balu T. Kuzhivelil and Thekkekara D. Babu, Journal of Complementary and Integrative Medicine,2(2021)1-7
  3. Preliminary assessment on phytochemical composition, cytotoxic and antitumor efficacy of Simarouba glauca leaf methanolic extract. Shaji E. Mathew, Smitha K. Ramavarma, Thekkekara Devassy Babu, Balu T. Kuzhivelil and Achuthan C. Raghavamenon, Annals of Phytomedicine 8,2 (2019)121-126
  4. In vitro cytotoxic and antiproliferative activities of Uvaria narum seed oil (UNSO). Smitha K Ramavarma, Ansa P Unnikrishnan, Babu. T. Devassy and Achuthan C Raghavamenon, International Journal of Advanced Research, 6 (2018) 912-916.
  5. GC-MS profiling of Petroleum ether subfraction exhibiting antitumor efficacy of Uvaria narum Smitha K Ramavarma, Thekkekara D Babu and Achuthan C Raghavamenon, Amala Research Bulletin 38 (2018) 76-82.
  6. Safety evaluation of Neera, a non-alcoholic drink from coconut inflorescence in mice. Silpa Prabha, Edappilly M Shaji, Smitha K Ramavarma, Indu M, Suseela, Meera Nair, Chennattu M Pareeth, Balu T Kuzhivelil and Thekkekara D Babu, Amala Research Bulletin, 38 (2018) 95-104
  7. Phytochemical composition and antioxidant properties of Uvaria macropoda Hook f & Thoms. Smitha K Ramavarma, Indu M Suseela, Shaji E Mathew, Arunaksharan Narayanankutty,Ramya M Kuttappan, Thekkekara D Babu and Achuthan C Raghavamenon, , Amala Research Bulletin, 37 (2017) 82-88.
  8. Acute and sub-acute toxicity evaluation of aqueous fraction of methanolic extract of Desmodium gyrans (DGMAF) in rats, M S Indu, Edappilly M Shaji, Smitha K Ramavarma, Silpa Prabha, Nair Meera,Ramya M Kuttappan, Achuthan C Raghavamenon and Jose Padikkala, Amala Research Bulletin, 37 (2017)38-44.
  9. Comparative study on phytochemical, physiochemical and antioxidant properties of Sorghum bicolor and Triticum aestivum, Rincy.C.K, Ranjitha.P.C, Priyanka.K., Shahanas.M, Aiswarya .C.G, Aneesha.K, Aiswarya Das, Gayathri.C.V, Rahul Pramod K V, Smitha K, R, Annals of basic and applied sciences, 8,1 (2017) 79-87.
  10. In vitro screening for antioxidant properties of Uvaria narum wall leaves, Smitha K Ramavarma, Shaji E Mathew, Indu M. Suseela, Arunaksharan Narayanan kutty, Ramya M Kuttappan, Babu T Devassy, and Achuthan C Raghavamenon, Amala Research Bulletin, 36 (2016)141-149.
  11. Omega 3 fatty acids: Do they raise health concerns, Arunaksharan, N, Muneera V, Jeksy J.M., Smitha K.R., Indu M.S., Babu TD and Achuthan C.R, JSM Biochemistry & Molecular biology, 3,1 (2016)1-5.
  12. Deep fried edible oils disturb hepatic redox equilibrium and heightens lipotoxicity and hepatoteatosis in male Wistar rats, Arunaksharan N, Jeksy J. M., Indu M. S., Smitha K. R., Shaji E M, SP Illam, Babu T D and Achuthan C. R, Human and experimental toxicology, 36,9 (2016) 919-930.
  13. Study on antimicrobial and antioxidant potential of Biophytum sensitivum in three different solvents, Ruveena T N, Smitha K R, Ann Mesna P, Rini A A. South Indian Journal of Biological Sciences. 2,1(2016)1-8.
  14. Virgin coconut oil maintains redox status and improves glycemic conditions in high fructose fed rats. Arunaksharan N, Reshma K. M., Shabna K. A., Smitha K. R., Indu M. S., Jeksy J. M., Balu T. K. and Achuthan C. Raghavamenon Journal of food science and technology, 53,1(2016) 895-901.
  15. Antioxidant and antiproliferative activities of Uvaria narum seed oil (UNSO), Smitha K R, Ansa P U, Jeksy J M, Indu M S, Arunaksharan N, Babu T D and Achuthan C R. Amala Research Bulletin, 35, (2015) 107- 112.
  16. Vitamin E supplementation modulates the effect of Omega 3 fatty acids treatment in aged rats, Anagha K, Arunaksharan N, Jeksy J M, Indu M S, Smitha K R, Shaji E M, Ramya M K, Soorya P I, Balu T K and Achuthan C R. Amala Research Bulletin, 35 (2015) 84- 91.
  17. Desmodium gyrans DC modulates lipid trafficking in macrophages and improves functional HDL in rats, Indu M S, Arunaksharan N, Smitha K R, Jeksy J M, Vipin P S, Shaji E M, Ramya M K, Jose Padikkala and Achuthan C R Amala Research Bulletin, 35, (2015)143- 150.
  18. Influence of proportional variations of constituent plant extracts in a polyherbal formulation GSTC on hyperlipidemia, Jeksy M J, N Arunaksharan, M S Indu, K R Smitha, E M Shaji and Achuthan C R Amala Research Bulletin, 35 (2015) 193- 205.
  19. Preliminary phytochemical screening, cytotoxic and antitumor studies of Simarouba glauca (Laxmitaru), Shaji E M, Smitha K R, Arunaksharan N, Ramya M K, Babu T D, Balu T K and Achuthan C R, Amala Research Bulletin, 35 (2015)15- 23.
  20. Component authentication and standardization of an anti-atherosclerotic herbal Formulation-GSTC3, Jeksy J M, Indu M S, Smitha K R, Arunaksharan N and Achuthan C R, Pharmacognosy Journal 7,6 (2015) 339-343.
  21. Development of an anti-atherosclerotic polyherbal formulation: GSTC3, Jeksy J M, Merin B, Smitha K R, Indu M S, Jose P, Achuthan C. R. J Environ Pathol Toxicol Oncol. 34 (2015) 237-248.
  22. Virgin coconut oil supplementation ameliorates cyclophosphamide-induced systemic toxicity in mice, Nair SS, Manalil JJ, Ramavarma SK, Suseela IM, Thekkeppat A, Raghavamenon AC, Human and experimental toxicology, 35:2(2016)205-12.
  23. Virgin coconut oil as fatty acid source in high fructose/sucrose diet reduces hyperglycemia, associated dyslipidemia and oxidative stress in Wistar rats, Arunaksharan N, Reshma K M, Shabna A R, Indu M S, Smitha K R, Jeksy M J and Achuthan C R Amala research bulletin. 34 (2014) 83-91.
  24. Characterization of docosahexaenoic acid oxidation products and assessment of its carbonyl stress and cytotoxicity in vitro, Midhun K G, Arunaksharan N, Indu M S, Smitha K R, Babu T D and Achuthan C R, Amala research bulletin. 34, (2014),114-151.
  25. Cytotoxic potential and antitumor properties of Uvaria narum seed oil. Smitha K R, Ansa P U, and Achuthan C R, Amala research bulletin.34(2014) 68-74.
  26. Phytochemical screening and in vitro cytotoxicity analysis of Uvaria narum (Dunal) wall. Smitha K R, Babu T D, Achuthan C R, Asian Journal of Phytomedicine and Clinical Research. 2 (2014) 40 – 47.
  27. Exploring antimicrobial and antioxidant activity of a traditional herbal medicine, Cynodon dactylon (l.) Pers. and its phytochemical screening. Smitha K R, Ruveena T N, Rini A, Ann M, World journal of pharmacy and pharmaceutical sciences,3 (2014)1744-1757.
  28. Virgin coconut oil protects mice from cyclophosphamide induced systemic toxicity. Suraja S, Jeksy M J, Smitha K R, Anjali T, Achuthan C R, Amala research bulletin. 33(2013) 159-170.
  29. Phytochemical analysis and determination of antitumor activity of petroleum ether leaf extract of Uvaria narum Smitha K R, Annu S M, Babu T D, Achuthan C. R. Amala research bulletin, 33 (2013) 101-106.
  30. Preliminary phytochemical screening and antioxidant properties of Centella asiatica. Smitha K.R, Ruveena T N., Neethu P, Nazeeha P, Liji K J., Nima B, Neethu N International Journal of Universal Pharmacy and Life Sciences. 3 (2013) 41-48.
  31. Evaluation of antioxidant activity of Tetragonia tetragonoides, Cichorium intybus and Taraxacum officinale, Smitha K R, Sudha G. Advanced Biotech, 11,10 (2012) 35-41.
  32. Antioxidant activity of Spergula arvensis, Amaranthus spinosus and Spinacia oleracea. Smitha K R, Sudha G, International Journal of Universal Pharmacy and Life Sciences, 1 (2011), 50-65.
Seminar / Conference Proceedings
  1. Pharmacological potential of Uvaria narum (Dunal) Wall. with special reference to anticancer properties. Smitha K. Ramavarma, Annu M. Sony, Shaji E. Mathew, Indu M. Suseela, Ramya M. Kuttappan, Thekkekara D. Babu and Achuthan C. Raghavamenon (36th Annual Conference of Indian Association for Cancer Research (IACR) at Amala Cancer Research Centre, Thrissur, February 2017)
  2. Phytoconstituent analysis and assessment of cytotoxic and antitumor activities of narum Wall. seed oil, Smitha K R, Ansa P U, Babu T D and Achuthan C R, (33rd annual convention of IACR organized by RGCB, Thiruvananthapuram, Srinivasa Ramanujan Institute for Basic sciences, and IACR, India at Kollam, February 2014).
  3. Phytochemical screening, TLC profiling and cytotoxicity analysis of Uvaria narum wall. Smitha K R, Babu T D and Achuthan C R (DST sponsored National Conference on Modern Trends in Zoological Research at St. Aloysius College, Elthuruth, Thrissur March 2014).
  4. Evaluation of antimicrobial and antioxidant potential of ethnolic and chloroformic extracts of Biophytum sensitivum, T N Ruveena, K R Smitha, Ann Mesna Pongathara and Rini Arif. (UGC sponsored National Seminar on Recent advances in Biotechnology at St Joseph’s college, Irinjalakuda November 2014.)
  5. Partial purification of anti-oxidant and anti-lipoxydase components from Baliospermum montanum. Smitha K R, Cecy F A, Zahara H, Archana A, Achuthan C R. (UGC sponsored National Symposium on Modern Biotechnology: Prospects and Challenges at KKTM Govt. College, Pullut, Kodungallur, Kerala, January 2013).
  6. Screening of antioxidant activities of indigenous plants and determination of efficacy of leaf extracts to prevent In vitro lipid peroxidation, Smitha K R and Dr.G.Sudha, (UGC sponsored National Seminar on Nanobiotechnology: A Global Perspective, at M.E.S College, Marampilly, Kerala March 2012).
  7. Comparative evaluation of antioxidant property in aqueous extracts of some unexploited green leafy vegetables of South India, Smitha K R and Dr. G. Sudha. (UGC sponsored National Seminar on Bioinformatics and Nanotechnology at Little Flower College, Guruvayur, Kerala, February 2012).
  8. Evaluation of free radical scavenging activity of a few medicinal plants from South India. Beena Jose, L.Joji Reddy, Dhanya K C, Smitha .K.R. (Souvenir of international symposium on innovations in free radical research and experimental therapeutics (Ifrret-2011) & 5th Annual convention of association of Biotechnology and Pharmacy at Karunya University, Coimbatore, Tamil Nadu, December 2011)
  9. Antioxidant activity of some green leafy vegetables. Smitha K R and Dr. G. Sudha, (UGC sponsored National seminar on emerging trends in Biopharmaceuticals at St. Mary’s College, Thrissur, Kerala August 2011).
Membership in Academic Bodies/ Organisations
  • Life member of Indian Association for Cancer Research (IACR)
  • Life member of Society for Biotechnologists (India)
  • Member in Board of Studies, UG Board of Studies of Biochemistry from 2020 onwards
Courses & Training Attended
  • Online Faculty Development Programme on ‘Outcome Based Education: Framing Questions Using Bloom’s Taxonomy’ by UGC – STRIDE, Mahatma Gandhi University, Kottayam in association with Internal Quality Assurance Cell, Sree Sankara College, Kalady from 21/06/2021 to 25/06/2021.
  • Faculty Development Programme on “Effective Teaching and Learning Through Moodle” by PG and Research Department of Physics combined with IQAC, Sree Narayana College, Kollam in association with the Kerala State Higher Education Council from 31/05/2021 to 04/05/2021.
  • Online Short-term Faculty Development Programme on “Towards a Digital Era of Teaching and Learning” by Kumbalathu Sankupillai Memorial Devaswom Board College, Sasthamcotta in collaboration with UGC HRDC University of Kerala from 12/8/2020 to 18/8/2020.
  • Online Short-term Faculty Development Programme on “Implementation of Information and Communication Technology in Teaching” by school of Legal Studies, Cochin University of Science and Technology in collaboration with the Kerala State Higher Education Council from 18/7/2020 to 24/7/2020.
  • Online training programme to chairman and members of board of studies under the faculty of science on the topic “CBCSS-UG regulation 2019” by MHRD teaching learning centre, University of Calicut from 6/07/2020 to 8/07/2020.
  • Online training programme on “Reference management system using free software Zotero “by Internal Quality Assurance Cell and LMS monitoring committee, Sree Neelakanda Govt. Sanskrit College, Pattambi from 22/05/2020 to 31/05/2020.
  • Online training programme on “Moodle based learning management system” by Internal Quality Assurance Cell and LMS monitoring committee, Sree Neelakanda Govt. Sanskrit College, Pattambi from 5/05/2020 to 14/05/2020.
  • An online training course on “Make and edit video classes“ by Internal Quality Assurance Cell of Christ College, Iringalakkuda 01/05/2020 to 05/05/2020.
  • Two weeks MOOC on “Online Learning and Content Development (OLCD)” by FLAIR Kerala and Directorate of Collegiate education, Kerala from 18/04/2020 to 02/05/2020.
  • Refresher Course in Experimental Techniques for Biological Sciences         sponsored by UGC-HRDC, University of Calicut from      06/02/2020 to 19/02/2020.
  • ARPIT Course for Career Advancement Scheme (CAS) promotion: Refresher Course on Teacher and Teaching in Higher Education by Savitribai Phule Pune University, AICTE, SWAYAM from 01/09/2019 to 31/12/2019.
  • AICTE approved FDP course ‘Genetic Engineering: Theory and Application by IIT Guwahati, AICTE, SWAYAM from         29/07/2019 to 18/10/2019.
  • 106th Orientation Programme sponsored by UGC, Human Resource Development Centre, University of Calicut on10/10/2019 to 30/10/2019.
  • Master Mentor Training Programme of Walk with Scholar at St Theresa’s college, by Directorate of Collegiate education, The Kerala State Higher Education Council on 05/09/2019.
  • Syllabus revision workshop of BSc Biochemistry CUSS 2019 regulation, by Board of studies of Biochemistry, University of Calicut at Department of Life sciences, University of Calicut on 8/5/2019
  • Science Academics Lecture workshop on “Progress and prospects of Biotechnology” Organized by Department of Biotechnology, St Joseph’s college, Irinjalakuda on 26-27 June 2014
  • Five-day workshop on curriculum design for Biochemistry course-credit semester system (UG) held under joint auspices of Kerala State Higher Education Council and University of Calicut at Department of Life sciences, University of Calicut.2009.