Profile

Dr. UMADEVI. DMSc, MPhil, PhDAssistant Professor and Head (i/c)E-mail : This email address is being protected from spambots. You need JavaScript enabled to view it. Phone : +91 9747949993

 

Profile

Areas of interest

Neuropeptides and neurohormones ,Cancer biology

Professional Experience

November 2013-January 2014 : Post doctoral fellow –cum -Reasearch Scientist in the Centre for Nanosciences and Molecular medicine, Amrita institute of Medical sciences and Research centre (AIMS), Kochi.

June 2012-January 2013 : Lecturer in Biochemistry, Department of Microbiology, GEMS Arts and Science College, Ramapuram, Malappuram.

June 2007-January 2008 : Lecturer in Biochemistry, Department of Botany and Biotechnology, A. J. College of Science and Technology, Thiruvananthapuram.

July 2005-May 2006 : Lecturer in Biochemistry, Department of Zoology, ST. Stephen’s College, Pathanapuram, Kollam.

Research experience

Post Doctoral Work :PDF at Centre for Nanosciences and Molecular medicine, Amrita, Cochin [Areas of research : 1)Humanization of anti EGFR antibody against ovarian carcinoma, 2)Fusion transcripts in cancer; potential to inhibit by RNAi].

PhD work : Calicut University, Malappuram (Area of research : Identification and characterization of an adipokinetic neuropeptide from the mango leaf webber, Orthaga exvinacea

MPhil work : Bharathiyar University (Area of research : Emodin mediated down regulation of matrix metalloproteinases in SNP induced colon cancer cells at Sree Chitra Tirunal Institute of Medical sciences, Thiruvananthapuram)

Research experience in mammalian cell culture (adherent cells and suspension cells), hybridoma cell culture, antibody purification, fragmentation and nanoconjugation, HPLC, SDS PAGE, Western blotting, ELISA, Enzyme kinetics and activity assays, protein extraction, purification and characterization, DNA and RNA extraction, cDNA synthesis, PCR, RT-PCR, qPCR, PAPD-PCR, AGE, plasmid isolation, transfection, transformation, U.V-Visible Spectrophotometry, fluorescent microscopy.

Publications

Books

Umadevi, D., Gokuldas M. (2013). Adipokinetic neuropeptide hormones of Orthaga exvinacea Hampson. Publisher: Lambert Academic Publishers, GermanyISBN:978-3-659-31258-8

Umadevi, D. (2013). Role of Matrix metalloproteinase in cancer development and progression. Publisher: Lambert Academic Publishers, GermanyISBN:978-3-659-36055-8

Journals

Umadevi, D., Uma. C. (2011). Expression of MMP2 and MMP9 (Gelatinases A and B) in Human Colon Cancer Cells. Journal of Applied Biochemistry and Biotechnology, 165:1245-1252

Umadevi, D., Uma. C. (2011). Emodin mediated down regulation of Matrix metalloproteinases (MMPs) in SNP treated colon cancer cells. Research Journal of Pharmaceutical, Biological and Chemical Sciences, 2 (2), 869-876

Umadevi, D., Gokuldas M., Ajaykumar, A.P. (2012). Hyperlipaemic and hyperglycaemic effects of a metabolic peptide hormone from the neuronal tissues of the mango leaf webber Orthaga exvinacea Hampson. International Research Journal of Pharmacy, 3 (2), 271-276

Gokuldas M., Ajaykumar, A.P., Umadevi, D., V.S. Binitha., K.M. Ismail, K.A. Rashed. (2013). Identification of Adipokinetic neuropeptide from the rice grasshopper Hieroglyphus Banian. Journal of Entomology, 10 (2): 95-102

Umadevi, D., Uma. C (2012). Effect of Lycopersicon esculentum, Citrus Limon and Daonil on renal calculi. Journal of Global Pharma Technology, 7 (4): 28-30

Umadevi, D., K.U.M.A. Rafeeq., Ajaykumar, A.P., K.M. Ismail, K.A. Rashed., Gokuldas M., (2013). Identification and structural characterization of a hyperlipemic neuropeptide from the mango leaf webber, Orthaga exvinacea Hampson. American journal of Biochemistry and Molecular biology, 3 (3): 304-313

Umadevi, D., Gokuldas M. (2014). Gene sequence of the adipokinetic hormone of the mango leaf webber, Orthaga exvinacea. International Journal of Life Sciences and Pharma Research, 3 (4): 226-234

Smitha M. Xavier., Umadevi, D. (2014). Anticancerous activity of resveratrol, on human colon tumor (HCT) cell lines. International journal of science innovations and discoveries. 4 (1): 1-7

Smitha M. Xavier., Umadevi, D. (2014). Hepatoprotective effect of Gotu Kola (Centella Asiatica Linn.) on carbon tetra chloride induced liver injury in rats. International research journal of pharmacy, 5 (12): 929-931

Umadevi, D., K.U.M.A. Rafeeq; Gokuldas M. (2014). Identification of a metabolic peptide hormone from the neurohaemal tissues of Orthaga exvinacea. Acta Biologica Indica, 3(1): 485-493

GenBank deposit

Gene Sequences Deposited in GenBank of NCBI. Adipokinetic hormone gene sequence of Orthaga exvinacea Hampson. GeneBank accession No: HQ269419 (2010).

Presentations

Presentations

Targeting Matrix metalloproteinases on tumor progression: Focus on human colonic carcinoma (Oral). National seminar, Department of Zoology, Sree Neelakanta Sanskrit College, Pattambi (2015).

Primary structure of an adipokinetic neuropeptide from the mango leaf webber, Orthaga exvinacea (Oral). National seminar, Department of Biotechnology, EMEA College, Malappuram (2015).

Hyperlipaemic effects of a metabolic neuropeptide hormone on vertebrate liver (Oral). National conference on “Advances in Entomological Research” at University of Calicut (2014).

Identification of a metabolic neuropeptide hormone from the neurohaemal tissues of a mango leaf webber Orthaga exvinacea Hampson (Oral). National conference on “Biological conference 2013” at University of Calicut (2013).

Matrix metalloproteinases (MMPs) and Colon cancer (Oral). National conference on “Recent Trends in Animal Physiology” at University of Mysore, Manasagangotri (2009).

Effect of Lycopersicon Esculentum, Citrus limon and Daonil on Renal calculi (Oral). National conference on “Recent Trends in Medical Microbiology”at Karpagam Arts and science College, Coimbatore (2007).

Biodiversity of rice (oryza sativa) and sugar cane (saccharum officinarum) on rhizosphere pseudomonads (Oral). National seminar on “Biodiversity and Conservation’, Karpagam Arts and Science College (2007).

Biology of Interleukins-Implications for Cancer Therapy and Vaccine Design (Poster). National Symposium on “Recent Trends in the Research and Management of Cancer” at Avinashilingam Deemed University (2006).

Stem Cell Therapy in Diabetes (Oral). National seminar on “Challenging Diabetes”at Karpagam Arts and Science College, Coimbatore (2006).

EGFR Trafficking (Poster). National seminar on “The Facets of Biotechnology” at CMS College for Science and Commerce, Coimbatore (2006).

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